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Index > Protein center > VAMP2(Gene name) > Human
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  • VAMP2 (Gene name),
  • Vesicle-associated membrane protein 2 (Protein name ),  VAMP2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VAMP2(SYB2);
    Protein name:
    Vesicle-associated membrane protein 2(VAMP-2);
    Alternative:
    Synaptobrevin-2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Interacts with BVES and STX4 (By similarity). Interacts with VAPA and VAPB.
    Function:
    Involved in the targeting and/or fusion of transport vesicles to their target membrane.
    Subcellular Location:
    Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane Single-pass type IV membrane protein Cell junction synapse synaptosome Neuronal synaptic vesicles.
    Protein Attributes:
    Sequence length:
    116
    Sequence:
    50:
    MSATAATAPP | AAPAGEGGPP | APPPNLTSNR | RLQQTQAQVD | EVVDIMRVNV | 
    100:
    DKVLERDQKL | SELDDRADAL | QAGASQFETS | AAKLKRKYWW | KNLKMMIILG | 
    116:
    VICAIILIII | IVYFST
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human VAMP-2
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    ELISA Kit for Human VAMP-2
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    ELISA Kit for Human VAMP-2
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    ELISA Kit for Human VAMP-2
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    E11932m
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    CLIA Kit for Human VAMP-2
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    U11932h
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    Packing:
    96T
    CLIA Kit for Human VAMP-2
    Cat.:
    U11932b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human VAMP-2
    Cat.:
    U11932m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human VAMP-2
    Cat.:
    U11932r
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    Packing:
    96T
    Polyclonal Antibody for Human VAMP-2
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    P11932Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human VAMP-2
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    P11932Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human VAMP-2
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    P11932Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human VAMP-2
    Monoclonal Antibody for Human VAMP-2
    Monoclonal Antibody for Human VAMP-2
    Monoclonal Antibody for Human VAMP-2
    Monoclonal Antibody for Human VAMP-2
    Protein for Human VAMP-2
    Protein for Human VAMP-2
    Protein for Human VAMP-2
    Protein for Human VAMP-2

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    References
    1. 1.
      "Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2."
      Archer B.T. III , Oezcelik T. , Jahn R. , Francke U. , Suedhof T.C.
      J. Biol. Chem.265:17267-17273(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Expression of VAMP genes in human neutrophils."
      Nabokina S.M. , Lazo P.A. , Mollinedo F.
      Submitted (1998-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Peripheral blood.
    3. 3.
      "Genomic structure of human SYB2 gene."
      Taruscio D. , Zoraqi K.G. , Falbo V.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Blood.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Cerebellum.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Neuroblastoma.
      tissue: Testis.
    7. 7.
      "Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2."
      Jagadish M.N. , Fernandez C.S. , Hewish D.R. , Macaulay S.L. , Gough K.H. , Grusovin J. , Verkuylen A. , Cosgrove L. , Alafaci A. , Frenkel M.J. , Ward C.W.
      Biochem. J.317:945-954(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    8. 8.
      "Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane."
      Kutay U. , Ahnert-Hilger G. , Hartmann E. , Wiedenmann B. , Rapoport T.A.
      EMBO J.14:217-223(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TOPOLOGY
    9. 9.
      "Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution."
      Hanson M.A. , Stevens R.C.
      Nat. Struct. Biol.7:687-692(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 34-89 IN COMPLEX WITH BOTB
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